Vitamin B15 (Synonyms: Pangamic Acid)

Cat. No.: HY-N7384: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-correcting agent. Vitamin B15 can be used for wide range of diseases.

For research use only. We do not sell to patients.

Vitamin B15 Chemical Structure

CAS No. : 20858-86-0

Size	Stock
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-correcting agent^[1]^[2]. Vitamin B15 can be used for wide range of diseases.

In Vivo

Vitamin B15 (Wistar rats; 2.5 mg/100 g of diet) increases the degree of fatty infiltration of the liver which is maintained at a stable level throughout the whole experiment^[1]^[3].
Vitamin B15 enriches in the rat diet reduced glutathione peroxidase (after one year) and also glutathione transferase (after 18 months) in the brains of the animals, thus impairing their antioxidative capacities^[1].
Vitamin B15 increase the cytochrome oxidase- and also succinate dehydrogenase-activity in certain rat tissues^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

281.26

Formula

C₁₀H₁₉NO₈

CAS No.

20858-86-0

Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)COC(CN(C)C)=O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (888.86 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5554 mL	17.7771 mL	35.5543 mL
5 mM	0.7111 mL	3.5554 mL	7.1109 mL
10 mM	0.3555 mL	1.7777 mL	3.5554 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Schneider D, et al. Studies on the chemical identity and biological functions of pangamic acid. Arzneimittelforschung. 1999 Apr;49(4):335-43. [Content Brief]

[2]. Zemskov AM, et al. Typical immune system responses to differential monotherapy with immune-correcting drugs. Fiziol Cheloveka. 2001 Jul-Aug;27(4):97-103. [Content Brief]

[3]. Ziemlański S, et al. Effect of long-term diet enrichment with selenium, vitamin E and vitamin B15 on the degree of fatty infiltration of the liver. Acta Physiol Pol. 1984 Jul-Aug;35(4):382-97. [Content Brief]

[4]. Vitamin B15

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.5554 mL	17.7771 mL	35.5543 mL	88.8857 mL
	5 mM	0.7111 mL	3.5554 mL	7.1109 mL	17.7771 mL
	10 mM	0.3555 mL	1.7777 mL	3.5554 mL	8.8886 mL
	15 mM	0.2370 mL	1.1851 mL	2.3703 mL	5.9257 mL
	20 mM	0.1778 mL	0.8889 mL	1.7777 mL	4.4443 mL
	25 mM	0.1422 mL	0.7111 mL	1.4222 mL	3.5554 mL
	30 mM	0.1185 mL	0.5926 mL	1.1851 mL	2.9629 mL
	40 mM	0.0889 mL	0.4444 mL	0.8889 mL	2.2221 mL
	50 mM	0.0711 mL	0.3555 mL	0.7111 mL	1.7777 mL
	60 mM	0.0593 mL	0.2963 mL	0.5926 mL	1.4814 mL
	80 mM	0.0444 mL	0.2222 mL	0.4444 mL	1.1111 mL
	100 mM	0.0356 mL	0.1778 mL	0.3555 mL	0.8889 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vitamin B1520858-86-0Pangamic AcidVitamin B 15Vitamin B-15OthersD-gluconodimethylaminoaceticdiisopropylammoniumdichloroacetateinfiltrationglutathioneperoxidasetransferaseInhibitorinhibitorinhibit

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