ω-Conotoxin MVIIC TFA

Cat. No.: HY-P0188A Purity: 99.88%: FAQs
Data Sheet SDS COA Handling Instructions

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ω-Conotoxin MVIIC TFA is a N- and P/Q-type Ca²⁺ channel blocker, significantly suppresses the 11-keto-βboswellic acid-mediated inhibition of glutamate release.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

ω-Conotoxin MVIIC TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 650	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1850	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of ω-Conotoxin MVIIC TFA:

ω-Conotoxin MVIIC Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

ω-Conotoxin MVIIC TFA is a N- and P/Q-type Ca²⁺ channel blocker, significantly suppresses the 11-keto-βboswellic acid-mediated inhibition of glutamate release^[1].

Molecular Weight

2863.27

Formula

C₁₀₆H₁₇₈N₄₀O₃₂S₇.C₂HF₃O₂

Appearance

Solid

Color

White to off-white

Sequence

Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2 (Disulfide bridge: Cys1-Cys16; Cys8-Cys20; Cys15-Cys26)

Sequence Shortening

CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2 (Disulfide bridge: Cys1-Cys16; Cys8-Cys20; Cys15-Cys26)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (260 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (113 KB) MS (208 KB)

Handling Instructions (2659 KB)

References

[1]. Cheng Wei Lu, et al. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta Med. 2020 Apr;86(6):434-441. [Content Brief]