10-Hydroxy-2-decenoic acid (Synonyms: 10-HDA)

Cat. No.: HY-W592871 Purity: 99.99%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans.

For research use only. We do not sell to patients.

10-Hydroxy-2-decenoic acid Chemical Structure

CAS No. : 765-01-5

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	In-stock	Estimated Time of Arrival: December 31
Solid
25 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

186.25

Formula

C₁₀H₁₈O₃

CAS No.

765-01-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)/C=C/CCCCCCCO

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Animals

Royal Jelly

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 250 mg/mL (1342.28 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3691 mL	26.8456 mL	53.6913 mL
5 mM	1.0738 mL	5.3691 mL	10.7383 mL
10 mM	0.5369 mL	2.6846 mL	5.3691 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (266 KB) SDS (0 KB)

COA (240 KB) HNMR (243 KB) RP-HPLC (212 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Yoko Honda, et al. 10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling. J Aging Res. 2015:2015:425261. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.3691 mL	26.8456 mL	53.6913 mL	134.2282 mL
	5 mM	1.0738 mL	5.3691 mL	10.7383 mL	26.8456 mL
	10 mM	0.5369 mL	2.6846 mL	5.3691 mL	13.4228 mL
	15 mM	0.3579 mL	1.7897 mL	3.5794 mL	8.9485 mL
	20 mM	0.2685 mL	1.3423 mL	2.6846 mL	6.7114 mL
	25 mM	0.2148 mL	1.0738 mL	2.1477 mL	5.3691 mL
	30 mM	0.1790 mL	0.8949 mL	1.7897 mL	4.4743 mL
	40 mM	0.1342 mL	0.6711 mL	1.3423 mL	3.3557 mL
	50 mM	0.1074 mL	0.5369 mL	1.0738 mL	2.6846 mL
	60 mM	0.0895 mL	0.4474 mL	0.8949 mL	2.2371 mL
	80 mM	0.0671 mL	0.3356 mL	0.6711 mL	1.6779 mL
	100 mM	0.0537 mL	0.2685 mL	0.5369 mL	1.3423 mL

10-Hydroxy-2-decenoic acid Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

10-Hydroxy-2-decenoic acid765-01-510-HDAmTORMammalian target of Rapamycinlipid componentantitumor activityanti-inflammatory activityantiangiogenic activityInhibitorinhibitorinhibit

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