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  3. 5(6)-Carboxynaphthofluorescein

5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm).

For research use only. We do not sell to patients.

5(6)-Carboxynaphthofluorescein Chemical Structure

5(6)-Carboxynaphthofluorescein Chemical Structure

CAS No. : 128724-35-6

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Based on 1 publication(s) in Google Scholar

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Description

5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm)[1].

In Vitro

5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator, it is sensitive in the pH range from 6.6 to 8.6 with a pKa value of 7.6[1].
5(6)-Carboxynaphthofluorescein have fluorescence properties, with excitation wavelength=593 nm, emission spectrum=668 nm[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

476.44

Formula

C30H20O7

CAS No.
Appearance

Solid

Color

Brown to black

SMILES

OC1=CC2=CC=C3C4(C(C=CC=C5)=C5C(O4)=O)C6=CC=C(C=C(O)C=C7)C7=C6OC3=C2C=C1.CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (262.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0989 mL 10.4945 mL 20.9890 mL
5 mM 0.4198 mL 2.0989 mL 4.1978 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0989 mL 10.4945 mL 20.9890 mL 52.4725 mL
5 mM 0.4198 mL 2.0989 mL 4.1978 mL 10.4945 mL
10 mM 0.2099 mL 1.0495 mL 2.0989 mL 5.2473 mL
15 mM 0.1399 mL 0.6996 mL 1.3993 mL 3.4982 mL
20 mM 0.1049 mL 0.5247 mL 1.0495 mL 2.6236 mL
25 mM 0.0840 mL 0.4198 mL 0.8396 mL 2.0989 mL
30 mM 0.0700 mL 0.3498 mL 0.6996 mL 1.7491 mL
40 mM 0.0525 mL 0.2624 mL 0.5247 mL 1.3118 mL
50 mM 0.0420 mL 0.2099 mL 0.4198 mL 1.0495 mL
60 mM 0.0350 mL 0.1749 mL 0.3498 mL 0.8745 mL
80 mM 0.0262 mL 0.1312 mL 0.2624 mL 0.6559 mL
100 mM 0.0210 mL 0.1049 mL 0.2099 mL 0.5247 mL
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5(6)-Carboxynaphthofluorescein Related Classifications

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Product Name:
5(6)-Carboxynaphthofluorescein
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HY-D1677
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