Amprolium hydrochloride

Cat. No.: HY-B0937A Purity: 99.11%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Amprolium hydrochloride is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake it prevents carbohydrate synthesis.

For research use only. We do not sell to patients.

Amprolium hydrochloride Chemical Structure

CAS No. : 137-88-2

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
250 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Amprolium hydrochloride:

Amprolium Get quote
Amprolium-d₇ bromide hydrobromide Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Coccidia

Molecular Weight

315.24

Formula

C₁₄H₂₀Cl₂N₄

CAS No.

137-88-2

Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=CC=[N+]1CC2=CN=C(CCC)N=C2N.[Cl-].Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 200 mg/mL (634.44 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1722 mL	15.8609 mL	31.7219 mL
5 mM	0.6344 mL	3.1722 mL	6.3444 mL
10 mM	0.3172 mL	1.5861 mL	3.1722 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (317.22 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.11%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (248 KB) LCMS (109 KB)

Handling Instructions (2659 KB)

References

[1]. Iqbal A, et al. Antiparasitic efficacy of Artemisia absinthium, toltrazuril and amprolium against intestinal coccidiosis in goats. J Parasit Dis. 2013 Apr;37(1):88-93. [Content Brief]

[2]. Lindsay DS, et al. Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice. J Parasitol. 1990 Apr;76(2):177-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.1722 mL	15.8609 mL	31.7219 mL	79.3047 mL
	5 mM	0.6344 mL	3.1722 mL	6.3444 mL	15.8609 mL
	10 mM	0.3172 mL	1.5861 mL	3.1722 mL	7.9305 mL
	15 mM	0.2115 mL	1.0574 mL	2.1148 mL	5.2870 mL
	20 mM	0.1586 mL	0.7930 mL	1.5861 mL	3.9652 mL
	25 mM	0.1269 mL	0.6344 mL	1.2689 mL	3.1722 mL
	30 mM	0.1057 mL	0.5287 mL	1.0574 mL	2.6435 mL
	40 mM	0.0793 mL	0.3965 mL	0.7930 mL	1.9826 mL
	50 mM	0.0634 mL	0.3172 mL	0.6344 mL	1.5861 mL
	60 mM	0.0529 mL	0.2643 mL	0.5287 mL	1.3217 mL
	80 mM	0.0397 mL	0.1983 mL	0.3965 mL	0.9913 mL
	100 mM	0.0317 mL	0.1586 mL	0.3172 mL	0.7930 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.