2. Anti-infection
  3. Penicillin-binding protein (PBP) Bacterial Antibiotic
  4. Ceftizoxime sodium

Ceftizoxime sodium  (Synonyms: SKF-88373)

Cat. No.: HY-B1596A Purity: 99.77%
COA Handling Instructions

Molarity Calculator

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

For research use only. We do not sell to patients.

Ceftizoxime sodium Chemical Structure

Ceftizoxime sodium Chemical Structure

CAS No. : 68401-82-1

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
50 mg USD 60 In-stock
100 mg USD 96 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ceftizoxime sodium:

Ceftizoxime sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Ceftizoxime sodium

View All Antibiotic Isoform Specific Products:

View All Isoforms
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

IC50 & Target

β-lactam

 

In Vitro

Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ceftizoxime sodium Related Antibodies
Clinical Trial
Molecular Weight

405.38

Formula

C13H12N5NaO5S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (246.68 mM; Need ultrasonic)

DMSO : 15 mg/mL (37.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4668 mL 12.3341 mL 24.6682 mL
5 mM 0.4934 mL 2.4668 mL 4.9336 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.4668 mL 12.3341 mL 24.6682 mL 61.6705 mL
5 mM 0.4934 mL 2.4668 mL 4.9336 mL 12.3341 mL
10 mM 0.2467 mL 1.2334 mL 2.4668 mL 6.1671 mL
15 mM 0.1645 mL 0.8223 mL 1.6445 mL 4.1114 mL
20 mM 0.1233 mL 0.6167 mL 1.2334 mL 3.0835 mL
25 mM 0.0987 mL 0.4934 mL 0.9867 mL 2.4668 mL
30 mM 0.0822 mL 0.4111 mL 0.8223 mL 2.0557 mL
H2O 40 mM 0.0617 mL 0.3084 mL 0.6167 mL 1.5418 mL
50 mM 0.0493 mL 0.2467 mL 0.4934 mL 1.2334 mL
60 mM 0.0411 mL 0.2056 mL 0.4111 mL 1.0278 mL
80 mM 0.0308 mL 0.1542 mL 0.3084 mL 0.7709 mL
100 mM 0.0247 mL 0.1233 mL 0.2467 mL 0.6167 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Ceftizoxime sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ceftizoxime68401-82-1SKF-88373SKF88373SKF 88373Penicillin-binding protein (PBP)BacterialAntibioticInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Ceftizoxime sodium
Cat. No.:
HY-B1596A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.