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  2. Disease Research Fields Plants Alkaloids Phenols
  3. Other Diseases other families Isoquinoline Alkaloids Monophenols
  4. Columbamine

Columbamine  (Synonyms: Columbamin; Dehydroisocorypalmine)

Cat. No.: HY-N0926 Purity: 98.38%
COA Handling Instructions

Columbamine is a quaternary isoquinoline alkaloid extracted from plants.

For research use only. We do not sell to patients.

Columbamine Chemical Structure

Columbamine Chemical Structure

CAS No. : 3621-36-1

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 198 In-stock
Solution
10 mM * 1 mL in DMSO USD 198 In-stock
Solid
5 mg USD 180 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Columbamine is a quaternary isoquinoline alkaloid extracted from plants.

Molecular Weight

338.38

Formula

C20H20NO4

CAS No.
Appearance

Solid

Color

Light yellow to orange

SMILES

COC1=C(OC)C2=C[N+]3=C(C4=CC(O)=C(OC)C=C4CC3)C=C2C=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 23 mg/mL (67.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9553 mL 14.7763 mL 29.5526 mL
5 mM 0.5911 mL 2.9553 mL 5.9105 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.70%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9553 mL 14.7763 mL 29.5526 mL 73.8814 mL
5 mM 0.5911 mL 2.9553 mL 5.9105 mL 14.7763 mL
10 mM 0.2955 mL 1.4776 mL 2.9553 mL 7.3881 mL
15 mM 0.1970 mL 0.9851 mL 1.9702 mL 4.9254 mL
20 mM 0.1478 mL 0.7388 mL 1.4776 mL 3.6941 mL
25 mM 0.1182 mL 0.5911 mL 1.1821 mL 2.9553 mL
30 mM 0.0985 mL 0.4925 mL 0.9851 mL 2.4627 mL
40 mM 0.0739 mL 0.3694 mL 0.7388 mL 1.8470 mL
50 mM 0.0591 mL 0.2955 mL 0.5911 mL 1.4776 mL
60 mM 0.0493 mL 0.2463 mL 0.4925 mL 1.2314 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Columbamine
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HY-N0926
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