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  4. Gadoteridol

Gadoteridol  (Synonyms: SQ-32692; Gd-HP-DO3A)

Cat. No.: HY-B0933 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Gadoteridol is a gadolinium-based magnetic resonance imaging (MRI) contrast agent, used in the imaging of the central nervous system.

For research use only. We do not sell to patients.

Gadoteridol Chemical Structure

Gadoteridol Chemical Structure

CAS No. : 120066-54-8

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 39 In-stock
Solution
10 mM * 1 mL in Water USD 39 In-stock
Solid
5 mg USD 32 In-stock
10 mg USD 45 In-stock
50 mg USD 90 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Gadoteridol:

Gadoteridol Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Gadoteridol

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Gadoteridol is a gadolinium-based magnetic resonance imaging (MRI) contrast agent, used in the imaging of the central nervous system[1].

In Vivo

Gadoteridol (1 mM; intracerebral injection; once) enhances distribution of rAAV1 in the rat hippocampus[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats (3 -5 months)[1]
Dosage: 1 mM/rat
Administration: Intracerebral injection, once, co-infused with rAAV1 or AAV5
Result: Increased the transduction efficiency of AAV1 but not AAV5.
Clinical Trial
Molecular Weight

557.68

Formula

C17H28GdN4O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1O[Gd+3]2([N]3(CC4)CC5=O)([N]6(CC7)CC([O-]2)=O)([N]47CC8=O)([O-]8)([O-]5)[N](CC6)(CC3)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 280 mg/mL (502.08 mM)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7931 mL 8.9657 mL 17.9314 mL
5 mM 0.3586 mL 1.7931 mL 3.5863 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (179.31 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (261 KB) Elemental Analysis Report (119 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7931 mL 8.9657 mL 17.9314 mL 44.8286 mL
5 mM 0.3586 mL 1.7931 mL 3.5863 mL 8.9657 mL
10 mM 0.1793 mL 0.8966 mL 1.7931 mL 4.4829 mL
15 mM 0.1195 mL 0.5977 mL 1.1954 mL 2.9886 mL
20 mM 0.0897 mL 0.4483 mL 0.8966 mL 2.2414 mL
25 mM 0.0717 mL 0.3586 mL 0.7173 mL 1.7931 mL
30 mM 0.0598 mL 0.2989 mL 0.5977 mL 1.4943 mL
40 mM 0.0448 mL 0.2241 mL 0.4483 mL 1.1207 mL
50 mM 0.0359 mL 0.1793 mL 0.3586 mL 0.8966 mL
60 mM 0.0299 mL 0.1494 mL 0.2989 mL 0.7471 mL
80 mM 0.0224 mL 0.1121 mL 0.2241 mL 0.5604 mL
100 mM 0.0179 mL 0.0897 mL 0.1793 mL 0.4483 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Gadoteridol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gadoteridol120066-54-8SQ-32692 Gd-HP-DO3ASQ32692SQ 32692Biochemical Assay ReagentsMRImagnetic resonance imagingcentral nervous systemrAAV1hippocampusInhibitorinhibitorinhibit

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