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  5. Ingenol-5,20-acetonide

Ingenol-5,20-acetonide is an intermediate from ingenol for synthesis of ingenoids; improved stability compared to ingenol.

For research use only. We do not sell to patients.

Ingenol-5,20-acetonide Chemical Structure

Ingenol-5,20-acetonide Chemical Structure

CAS No. : 77573-43-4

Size Price Stock Quantity
1 mg USD 165 In-stock
5 mg USD 495 In-stock
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Description

Ingenol-5,20-acetonide is an intermediate from ingenol for synthesis of ingenoids; improved stability compared to ingenol.

Molecular Weight

388.50

Formula

C23H32O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@](OC(C)(C)OC1)([H])C1=C[C@@]2([H])[C@H](C3(C)C)[C@H]3C[C@H]4C)([C@H]5O)[C@]4(C=C5C)C2=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (128.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5740 mL 12.8700 mL 25.7400 mL
5 mM 0.5148 mL 2.5740 mL 5.1480 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.73%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5740 mL 12.8700 mL 25.7400 mL 64.3501 mL
5 mM 0.5148 mL 2.5740 mL 5.1480 mL 12.8700 mL
10 mM 0.2574 mL 1.2870 mL 2.5740 mL 6.4350 mL
15 mM 0.1716 mL 0.8580 mL 1.7160 mL 4.2900 mL
20 mM 0.1287 mL 0.6435 mL 1.2870 mL 3.2175 mL
25 mM 0.1030 mL 0.5148 mL 1.0296 mL 2.5740 mL
30 mM 0.0858 mL 0.4290 mL 0.8580 mL 2.1450 mL
40 mM 0.0644 mL 0.3218 mL 0.6435 mL 1.6088 mL
50 mM 0.0515 mL 0.2574 mL 0.5148 mL 1.2870 mL
60 mM 0.0429 mL 0.2145 mL 0.4290 mL 1.0725 mL
80 mM 0.0322 mL 0.1609 mL 0.3218 mL 0.8044 mL
100 mM 0.0257 mL 0.1287 mL 0.2574 mL 0.6435 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ingenol-5,20-acetonide
Cat. No.:
HY-N0869
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