2. Immunology/Inflammation
  3. CD73
  4. MethADP

MethADP  (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate)

Cat. No.: HY-112502 Purity: ≥99.0%
COA Handling Instructions

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MethADP is a specific CD73 inhibitor.

For research use only. We do not sell to patients.

MethADP Chemical Structure

MethADP Chemical Structure

CAS No. : 3768-14-7

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1 mg USD 250 Ask For Quote & Lead Time
5 mg USD 600 Ask For Quote & Lead Time

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MethADP Related Antibodies

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Description

MethADP is a specific CD73 inhibitor.

IC50 & Target

CD73[1].
In Vitro

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MethADP Related Antibodies
Molecular Weight

425.23

Formula

C11H17N5O9P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@@H](COP(O)(CP(O)(O)=O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (255 KB)

Handling Instructions (2659 KB)
References
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MethADP Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MethADP3768-14-7Adenosine 5'-(α,β-methylene)diphosphateCD73ecto-5′-nucleotidase, NT5EInhibitorinhibitorinhibit

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