2. Peptides
  3. Peptide M

Peptide M is a synthetic amino acid (18 amino acids in length which correspond to the amino acid positions 303-322 of bovine S-antigen: DTNLASSTIIKEGIDKTV), is capable of inducing experimental autoimmune uveitis in monkeys and Hartley guinea pigs as well as Lewis rats.

For research use only. We do not sell to patients.

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Peptide M Chemical Structure

Peptide M Chemical Structure

CAS No. : 110652-62-5

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Based on 1 publication(s) in Google Scholar

Peptide M Related Antibodies

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Description

Peptide M is a synthetic amino acid (18 amino acids in length which correspond to the amino acid positions 303-322 of bovine S-antigen: DTNLASSTIIKEGIDKTV), is capable of inducing experimental autoimmune uveitis in monkeys and Hartley guinea pigs as well as Lewis rats[1].

In Vitro

peptide M is immunogenic in man and provide additional support to the hypothesis that the amino acid sequence which corresponds to peptide M might be involved in uveitic conditions in man[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peptide M Related Antibodies
Molecular Weight

1905.11

Formula

C81H141N21O31
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Thr-Asn-Leu-Ala-Ser-Ser-Thr-Ile-Ile-Lys-Glu-Gly-Ile-Asp-Lys-Thr-Val
Sequence Shortening

DTNLASSTIIKEGIDKTV
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (52.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5249 mL 2.6245 mL 5.2490 mL
5 mM 0.1050 mL 0.5249 mL 1.0498 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5249 mL 2.6245 mL 5.2490 mL 13.1226 mL
5 mM 0.1050 mL 0.5249 mL 1.0498 mL 2.6245 mL
10 mM 0.0525 mL 0.2625 mL 0.5249 mL 1.3123 mL
15 mM 0.0350 mL 0.1750 mL 0.3499 mL 0.8748 mL
20 mM 0.0262 mL 0.1312 mL 0.2625 mL 0.6561 mL
25 mM 0.0210 mL 0.1050 mL 0.2100 mL 0.5249 mL
30 mM 0.0175 mL 0.0875 mL 0.1750 mL 0.4374 mL
40 mM 0.0131 mL 0.0656 mL 0.1312 mL 0.3281 mL
50 mM 0.0105 mL 0.0525 mL 0.1050 mL 0.2625 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peptide M110652-62-5OthersbovineSantigenautoimmuneuveitisInhibitorinhibitorinhibit

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