2. Metabolic Enzyme/Protease
  3. Xanthine Oxidase Endogenous Metabolite
  4. Phytic acid

Phytic acid  (Synonyms: Inositol hexaphosphate; SNF472 free acid)

Cat. No.: HY-N0814 Purity: ≥95.0%
COA Handling Instructions

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Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

For research use only. We do not sell to patients.

Phytic acid Chemical Structure

Phytic acid Chemical Structure

CAS No. : 83-86-3

Size Price Stock Quantity
Solvent
250 mg (757.5 mM * 500 μL in Water) USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Phytic acid:

Phytic acid Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Phytic acid

  • Biological Activity

  • Protocol

  • Purity & Documentation

  • References

  • Customer Review

Description

Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4].

IC50 & Target

Xanthine oxidase[3]
In Vitro

Phytic acid (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by phytic acid; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phytic acid Related Antibodies
Clinical Trial
Molecular Weight

660.04

Formula

C6H18O24P6
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=P(O)(O)O[C@H]([C@H]([C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O)OP(O)(O)=O)[C@H]([C@H]1OP(O)(O)=O)OP(O)(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (151.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 30 mg/mL (45.45 mM)

*"≥" means soluble, but saturation unknown.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

COA (261 KB)

Handling Instructions (2659 KB)
References
Animal Administration
[4]

Mice: MPTP (20 mg/kg/day, i.p.) is administrated for 5 days and animals are killed at 7 days later. Phytic acid (30 mg/kg/day, i.p.) or normalsaline is injected 4 days before MPTP administration and con-tinued until mice are killed, reaching a total treatment period of16 days[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.5151 mL 7.5753 mL 15.1506 mL 37.8765 mL
5 mM 0.3030 mL 1.5151 mL 3.0301 mL 7.5753 mL
10 mM 0.1515 mL 0.7575 mL 1.5151 mL 3.7876 mL
15 mM 0.1010 mL 0.5050 mL 1.0100 mL 2.5251 mL
20 mM 0.0758 mL 0.3788 mL 0.7575 mL 1.8938 mL
25 mM 0.0606 mL 0.3030 mL 0.6060 mL 1.5151 mL
30 mM 0.0505 mL 0.2525 mL 0.5050 mL 1.2625 mL
40 mM 0.0379 mL 0.1894 mL 0.3788 mL 0.9469 mL
DMSO 50 mM 0.0303 mL 0.1515 mL 0.3030 mL 0.7575 mL
60 mM 0.0253 mL 0.1263 mL 0.2525 mL 0.6313 mL
80 mM 0.0189 mL 0.0947 mL 0.1894 mL 0.4735 mL
100 mM 0.0152 mL 0.0758 mL 0.1515 mL 0.3788 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Phytic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phytic acid83-86-3Inositol hexaphosphateSNF472SNF 472SNF-472Xanthine OxidaseEndogenous MetaboliteXOInhibitorinhibitorinhibit

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