2. Signaling Pathways
  3. Antibody-drug Conjugate/ADC Related
  4. ADC Linker
  5. Disulfide Cleavable Linker Isoform

Disulfide Cleavable Linker

 

Disulfide Cleavable Linker Related Products (130):

Cat. No. Product Name Effect Purity
  • HY-118759
    DSP Crosslinker
    		98.73%
    DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-100216
    SPDP
    		≥98.0%
    SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
  • HY-12448
    SPDB
    		98.82%
    SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
  • HY-101151
    sulfo-SPDB
    sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-147118
    NHS-SS-Ph
    NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-129368
    SPDMV
    SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
  • HY-128926
    SPP
    SPP is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate.
  • HY-126530
    PPC-NB
    		99.90%
    PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC).
  • HY-133413
    DBCO-CONH-S-S-NHS ester
    DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • HY-129942
    S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
    S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes.
  • HY-126498
    PDEC-NB
    		99.69%
    PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
  • HY-140096
    Aminoethyl-SS-propionic acid
    		98.03%
    Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-140129
    NHS-SS-biotin
    		≥98.0%
    NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-135973
    BCN-SS-NHS
    BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • HY-133408
    4-Methyl-4-(methyldisulfanyl)pentanoic acid
    		99.97%
    4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-140116
    Boc-NH-ethyl-SS-propionic acid
    Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-140127
    Azide-C2-SS-C2-biotin
    		98.79%
    Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • HY-136039
    TCO-SS-amine
    TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-SS-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
  • HY-136133
    NHS-PEG2-SS-PEG2-NHS
    		≥98.0%
    NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-140105
    Azidoethyl-SS-ethylazide
    		98.79%
    Azidoethyl-SS-ethylazide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azidoethyl-SS-ethylazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.