2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. FAK
  5. FAK Degrader

FAK Degrader

FAK Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-139344
    FC-11
    		Degrader 99.70%
    FC-11 is a PROTAC FAK degrader (DC90: 1 nM) . FC-11 contains CRBN ligand Pomalidomide (HY-10984), linker and FAK ligand PF562271 (HY-10459). FC-11 degrades FAK in various cells, with DC50s of 310 pM in TM3, 80 pM in PA1, 330 pM in MDA-MB-436, 370 pM in LNCaP, and 40 pM in Ramos cells.