RSV

Respiratory syncytial virus

RSV

Related Products

RSV (Respiratory syncytial virus) is a leading cause of acute respiratory infections. RSV can exploit host immunity and cause a strong inflammatory response that leads to lung damage and virus dissemination. There is a single RSV serotype with two major antigenic subgroups, A and B.

RSV is a non-segmented negative-sense single-stranded enveloped RNA virus that belongs to the family of Paramyxoviridae, genus Pneumovirus, subfamily Pneumovirinae. Its 10 genes encode 11 proteins since two overlapping open reading frames in the M2 mRNA yield two distinct matrix proteins, M2-1 and M2-2. The viral envelope contains three proteins, the G glycoprotein, the fusion (F) glycoprotein, and the small hydrophobic (SH) protein. The RSV virus comprises five other structural proteins, the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1, and two non-structural proteins (NS1 and NS2).

RSV Related Products (67)
Recombinant Proteins (10)
Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-122587

AVG-233	Inhibitor	98.87%
AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L_1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC₅₀=0.14-0.31 μM). AVG-233 can be used for research of respiratory syncytial virus (RSV).

HY-P99804

Clesrovimab	Inhibitor	99.62%
Clesrovimab (MK1654) is a fully human, anti-RSV fusion (RSV F) glycoprotein monoclonal antibody. Clesrovimab has the potential for the research of respiratory syncytial virus infection.

HY-123475A

Sisunatovir hydrochloride	Inhibitor	98.54%
Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC₅₀s of 1.4 nM and 1.0 nM, respectively.

HY-109004

Enzaplatovir	Inhibitor	99.98%
Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection.

HY-P99586

Suptavumab	Inhibitor
Suptavumab (REGN2222) is a human monoclonal antibody. Suptavumab can bind and block a conserved epitope on RSV A and B subtypes. Suptavumab can be used for the research of RSV infection.

HY-120632

BMS-433771	Inhibitor	99.96%
BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC₅₀ of 20 nM. BMS-433771 can be used for the research of respiratory tract disease.

HY-W013605A

4-Methoxycinnamaldehyde	Inhibitor	99.30%
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC₅₀ of 0.055 μg/mL.

HY-147346

Zelicapavir	Inhibitor	98.70%
Zelicapavir (RSV-IN-7) (example 253) is a RSV inhibitor (EC₅₀: < 0.4 μΜ).

HY-109004A

(S)-Enzaplatovir	Inhibitor	99.35%
(S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC₅₀ of 56 nM for respiratory syncytial viral (RSV) (patent WO2011094823A1 compound 77).

HY-11098

JNJ 2408068	Inhibitor
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg.

HY-126303

GS-443902	Inhibitor	99.87%
GS-443902 (GS-441524 triphosphate) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC₅₀s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

HY-12993A

RSV604 racemate	Inhibitor	98.60%
RSV604 (A-60444) racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.

HY-112673

RSV-IN-1	Inhibitor	99.95%
RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC₅₀ of 0.11 μM.

HY-149648

JNJ-8003	Inhibitor
JNJ-8003 is a potent inhibitor of RSV Polymerase. JNJ-8003 inhibits nucleotide polymerization of RNA transcription and replication at the early stages.

HY-142645

RSV-IN-2	Inhibitor
RSV-IN-2 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins (wild-type, EC₅₀ = 0.27 nM; D486N-mutant, EC₅₀ = 0.70 nM).

HY-145392

ACSS2-IN-1	Inhibitor
ACSS2-IN-1 is a potent ACSS2 inhibitor for the treatment of cancer.ACSS2-IN-1 (Cpmpound 1) is a potent ACSS2 inhibitor. ACSS2-IN-1 inhibits ACSS2 with the IC₅₀ of 0.01 nM to <1 nM. ACSS2-IN-1 can be used for the research of cancer.

HY-15455S1

Roflumilast-d₄ N-Oxide	Inhibitor	98.13%
Roflumilast-d₄ N-Oxide is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].

HY-142009

Antiviral agent 10	Inhibitor
Antiviral agent 10 is an anti-viral agent that can inhibit respiratory syncytial virus (RSV).

HY-100285

RD3-0028	Inhibitor
RD3-0028 is a potent and selective inhibitor of RSV replication with an EC₅₀ of 4.5 μM.

HY-126033

Sophoranol	Inhibitor
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC₅₀ of 10.4 μg/mL.

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RSV

RSV

RSV Related Products (67)

Recombinant Proteins (10)

Antibodies (1)

RSV Related Products (67):