2. Signaling Pathways
  3. Immunology/Inflammation
  4. STING
  5. STING Degrader

STING Degrader

STING Degraders (5):

Cat. No. Product Name Effect Purity
  • HY-157570
    Anti-inflammatory agent 70
    		Degrader
    Anti-inflammatory agent 70 (N-Me-SP23) is a STING protein degrader and inhibits the STING signaling pathway. Anti-inflammatory agent 70 has anti-inflammatory activity.
  • HY-158046
    UNC8899
    		Degrader
    UNC8899 is a VHL-recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8899 can be used for viral or bacterial infection research (Blue: VHL ligand, Black: linker; Pink: STING inhibitor).
  • HY-162331
    STING Degrader-1
    		Degrader
    STING Degrader-1 (compound 2) is a potent STING degrader that covalently binds to STING and E3 ligase. STING Degrader-1 induces STING degradation through a ubiquitin-proteasome system-dependent pathway.
  • HY-158048
    UNC9036
    		Degrader
    UNC9036 is a PROTAC-based STING degrader, with a DC50 of 227 nM. UNC9036-mediated STING degradation is proteasome and VHL dependent (Srtucture Note: Red, STING agonist diABZI (HY-112921A); Blue, VHL ligand VH032 (HY-120217); Black, linker).
  • HY-158047
    UNC8900
    		Degrader
    UNC8900 is a VHL recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8900 can be used for research of viral or bacterial infection. (Blue: VHL ligand, black: linker; Pink: STING inhibitor).