2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Wnt
  5. Wnt Degrader

Wnt Degrader

Wnt Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-127019
    Nigericin
    		Degrader
    Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC.