1. Membrane Transporter/Ion Channel
  2. BCRP
  3. YHO-13351

YHO-13351 is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.

For research use only. We do not sell to patients.

YHO-13351 Chemical Structure

YHO-13351 Chemical Structure

CAS No. : 1346753-00-1

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5 mg USD 80 Ask For Quote & Lead Time
10 mg USD 130 Ask For Quote & Lead Time

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Other Forms of YHO-13351:

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Description

YHO-13351 is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.

Molecular Weight

579.73

Formula

C27H37N3O7S2

CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

N#C/C(C1=CC=C(OC)C(OC)=C1)=C\C2=CC=C(N3CCC(OC(CN(CC)CC)=O)CC3)S2.O=S(C)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (51.75 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7249 mL 8.6247 mL 17.2494 mL
5 mM 0.3450 mL 1.7249 mL 3.4499 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7249 mL 8.6247 mL 17.2494 mL 43.1235 mL
5 mM 0.3450 mL 1.7249 mL 3.4499 mL 8.6247 mL
10 mM 0.1725 mL 0.8625 mL 1.7249 mL 4.3124 mL
15 mM 0.1150 mL 0.5750 mL 1.1500 mL 2.8749 mL
20 mM 0.0862 mL 0.4312 mL 0.8625 mL 2.1562 mL
25 mM 0.0690 mL 0.3450 mL 0.6900 mL 1.7249 mL
30 mM 0.0575 mL 0.2875 mL 0.5750 mL 1.4375 mL
40 mM 0.0431 mL 0.2156 mL 0.4312 mL 1.0781 mL
50 mM 0.0345 mL 0.1725 mL 0.3450 mL 0.8625 mL
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YHO-13351 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
YHO-13351
Cat. No.:
HY-12758
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