1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. (R)-Baclofen hydrochloride

(R)-Baclofen hydrochloride  (Synonyms: Arbaclofen hydrochloride; STX 209 hydrochloride)

Cat. No.: HY-17354A
Handling Instructions

(R)-Baclofen hydrochloride (Arbaclofen hydrochloride) is a selective GABAB receptor agonist.

For research use only. We do not sell to patients.

(R)-Baclofen hydrochloride Chemical Structure

(R)-Baclofen hydrochloride Chemical Structure

CAS No. : 63701-55-3

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Top Publications Citing Use of Products

2 Publications Citing Use of MCE (R)-Baclofen hydrochloride

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  • Purity & Documentation

  • References

  • Customer Review

Description

(R)-Baclofen hydrochloride (Arbaclofen hydrochloride) is a selective GABAB receptor agonist[1][2].

IC50 & Target

GABAB receptor[1]

In Vivo

(R)-Baclofen hydrochloride (STX 209 hydrochloride) suppresses audiogenic seizures in the Fmr1-knockout mouse on the seizure-resistant C57BL/6 background with an effective dose of 1 mg/kg[3].
Acute intraperitoneal administration of (R)-Baclofen hydrochloride significantly reduces the percent of mice displaying seizures (seizure incidence), with a minimum effective dose (MED) of 1.5 mg/kg[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

250.12

Formula

C10H13Cl2NO2

CAS No.
SMILES

ClC1=CC=C([C@](CC(O)=O)([H])CN)C=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(R)-Baclofen hydrochloride Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-Baclofen hydrochloride
Cat. No.:
HY-17354A
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