Anticancer agent 46

Cat. No.: HY-146030 Purity: 95.73%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Anticancer agent 46 (compound 2) is a potent anticancer agent. Anticancer agent 46 shows antiproliferative activity with an IC₅₀ of 0.986 µM for MGC803 cells. Anticancer agent 46 has the potential for the research of gastric cancer.

For research use only. We do not sell to patients.

Anticancer agent 46 Chemical Structure

CAS No. : 2426686-17-9

Size	Price	Stock	Quantity
5 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 62	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

319.81

Formula

C₁₅H₁₄ClN₃OS

CAS No.

2426686-17-9

Appearance

Solid

Color

Light yellow to yellow

SMILES

C/C(C1=CC(Cl)=CC=C1O)=N\NC(NC2=CC=CC=C2)=S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (390.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1269 mL	15.6343 mL	31.2686 mL
5 mM	0.6254 mL	3.1269 mL	6.2537 mL
10 mM	0.3127 mL	1.5634 mL	3.1269 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.73%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (245 KB) HNMR (254 KB) RP-HPLC (246 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Zhang XH, et al. Thiosemicarbazone-based lead optimization to discover high-efficiency and low-toxicity anti-gastric cancer agents. Eur J Med Chem. 2020 Aug 1;199:112349. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1269 mL	15.6343 mL	31.2686 mL	78.1714 mL
	5 mM	0.6254 mL	3.1269 mL	6.2537 mL	15.6343 mL
	10 mM	0.3127 mL	1.5634 mL	3.1269 mL	7.8171 mL
	15 mM	0.2085 mL	1.0423 mL	2.0846 mL	5.2114 mL
	20 mM	0.1563 mL	0.7817 mL	1.5634 mL	3.9086 mL
	25 mM	0.1251 mL	0.6254 mL	1.2507 mL	3.1269 mL
	30 mM	0.1042 mL	0.5211 mL	1.0423 mL	2.6057 mL
	40 mM	0.0782 mL	0.3909 mL	0.7817 mL	1.9543 mL
	50 mM	0.0625 mL	0.3127 mL	0.6254 mL	1.5634 mL
	60 mM	0.0521 mL	0.2606 mL	0.5211 mL	1.3029 mL
	80 mM	0.0391 mL	0.1954 mL	0.3909 mL	0.9771 mL
	100 mM	0.0313 mL	0.1563 mL	0.3127 mL	0.7817 mL