2. Induced Disease Models Products Metabolic Enzyme/Protease
  3. Immunology and Inflammatory Disease Models Endogenous Metabolite
  4. Paw Edema Models
  5. Arachidonic acid sodium salt

Arachidonic acid sodium salt  (Synonyms: Immunocytophyt sodium salt)

Cat. No.: HY-109590A
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Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function.

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Arachidonic acid sodium salt Chemical Structure

Arachidonic acid sodium salt Chemical Structure

CAS No. : 6610-25-9

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Description

Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Arachidonic acid (0.07%, 0.15% or 0.32% in diet; 4 weeks) sodium salt increases Arachidonic acid content in the paw, but has no effect on arthritis severity and PGE2 content of the paw in a rat arthritis model[1].
Induction of Paw Edema Model[2]
Background
Principle: Injecting arachidonic acid into the hind paws of rats can induce rapid and sustained inflammatory responses.
Specific Mmodeling Methods
Rats: Lewis • male •
Administration: 0.5% • s.c. • single dose
Note
Injection method: A single subcutaneous injection of Arachidonic acid in the right hind paw of male Lewis rats (144-241 g) with an injection volume of 0.10 mL (Arachidonic acid is dissolved in 0.2 M carbonate buffer, pH 8.43-8.56 ).


Modeling Indicators
Appearance Monitoring: Significant edema became apparent within 5 minutes, and the reaction reached its peak at 1 hour after injection.
Opposite Product(s): Phenidone (HY-W010144); SK-F86002 (HY-12511)

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Lew rats (4-week-old) induced arthritis[1]
Dosage: 0.07%, 0.15% or 0.32% in diet (w/w)
Administration: 4 weeks
Result: The Arachidonic acid content of phospholipids in the paw was significantly elevated in a dose-dependent manner.
Molecular Weight

326.45

Formula

C20H31NaO2
CAS No.
SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[Na])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Arachidonic acid sodium salt Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Arachidonic acid6610-25-9ImmunocytophytEndogenous Metabolitepolyunsaturated fatty acidbiomembranescognitive responsecardiovascular functionInhibitorinhibitorinhibit

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