2. Vitamin D Related/Nuclear Receptor
  3. Progesterone Receptor
  4. Asoprisnil

Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human.

For research use only. We do not sell to patients.

Asoprisnil Chemical Structure

Asoprisnil Chemical Structure

CAS No. : 199396-76-4

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1 mg USD 170 In-stock
5 mg USD 435 Get quote
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Based on 1 publication(s) in Google Scholar

Asoprisnil Related Antibodies

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Description

Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human[1].

Clinical Trial
Molecular Weight

449.58

Formula

C28H35NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@@](OC)(CC[C@]1([C@@]3(CCC4=CC(CCC4=C3[C@H](C2)C5=CC=C(C=C5)/C=N/O)=O)[H])[H])COC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 45 mg/mL (100.09 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2243 mL 11.1215 mL 22.2430 mL
5 mM 0.4449 mL 2.2243 mL 4.4486 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.30%

COA (252 KB) LCMS (151 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2243 mL 11.1215 mL 22.2430 mL 55.6075 mL
5 mM 0.4449 mL 2.2243 mL 4.4486 mL 11.1215 mL
10 mM 0.2224 mL 1.1121 mL 2.2243 mL 5.5607 mL
15 mM 0.1483 mL 0.7414 mL 1.4829 mL 3.7072 mL
20 mM 0.1112 mL 0.5561 mL 1.1121 mL 2.7804 mL
25 mM 0.0890 mL 0.4449 mL 0.8897 mL 2.2243 mL
30 mM 0.0741 mL 0.3707 mL 0.7414 mL 1.8536 mL
40 mM 0.0556 mL 0.2780 mL 0.5561 mL 1.3902 mL
50 mM 0.0445 mL 0.2224 mL 0.4449 mL 1.1121 mL
60 mM 0.0371 mL 0.1854 mL 0.3707 mL 0.9268 mL
80 mM 0.0278 mL 0.1390 mL 0.2780 mL 0.6951 mL
100 mM 0.0222 mL 0.1112 mL 0.2224 mL 0.5561 mL
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Asoprisnil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Asoprisnil199396-76-4J867J 867J-867Progesterone ReceptorNR3C3Inhibitorinhibitorinhibit

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