2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. BChE-IN-32

ChE-IN-32 (compound 5d) is a potent and selective hBChE inhibitor with an IC50 value of 0.109 µM. BChE-IN-32 shows cytotoxicity. BChE-IN-32 has the potential for the research of Alzheimer's disease.

For research use only. We do not sell to patients.

BChE-IN-32 Chemical Structure

BChE-IN-32 Chemical Structure

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BChE-IN-32 Related Antibodies

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Description

ChE-IN-32 (compound 5d) is a potent and selective hBChE inhibitor with an IC50 value of 0.109 µM. BChE-IN-32 shows cytotoxicity. BChE-IN-32 has the potential for the research of Alzheimer's disease[1].

IC50 & Target[1]

hBCHE

0.109 μM (IC50)

In Vitro

BChE-IN-32 (compound 5d) (0-200 µM) shows cytotoxicity with IC50s of 110.0, 42 µM for SH-SY5Y, HepG2 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BChE-IN-32 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: SH-SY5Y, HepG2 cells
Concentration: 0-200 µM
Incubation Time:
Result: Showed cytotoxicity with IC50s of 110.0, 42 µM for SH-SY5Y, HepG2 cells, respectively.
Molecular Weight

407.59

Formula

C26H37N3O
Unlabeled Cas

SMILES

O=C(N[C@@]1(C[C@H]2C3)C[C@@]3(C)C[C@@](C2)(C)C1)CNC4=C5CCCCC5=NC6=C4CCC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BChE-IN-32 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BChE-IN-32Cholinesterase (ChE)Alzheimer's diseaseSH-SY5YHepG2 cellsInhibitorinhibitorinhibit

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