Benzethonium-d₇ chloride

Name: Benzethonium-d 7 chloride
Brand: MedChemExpress
SKU: HY-B0942S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0942S Purity: 98.64%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

For research use only. We do not sell to patients.

Benzethonium-d<sub>7</sub> chloride Chemical Structure

Benzethonium-d₇ chloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Benzethonium-d₇ chloride:

Benzethonium chloride In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

455.12

Formula

C₂₇H₃₅D₇ClNO₂

Appearance

Solid

Color

White to light yellow

SMILES

CC(C)(C)CC(C1=CC=C(OCCOCC[N+](C)(C)C([2H])([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C=C1)(C)C.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (219.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1972 mL	10.9861 mL	21.9722 mL
5 mM	0.4394 mL	2.1972 mL	4.3944 mL
10 mM	0.2197 mL	1.0986 mL	2.1972 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.64%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (245 KB) HNMR (146 KB) RP-HPLC (185 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1972 mL	10.9861 mL	21.9722 mL	54.9306 mL
	5 mM	0.4394 mL	2.1972 mL	4.3944 mL	10.9861 mL
	10 mM	0.2197 mL	1.0986 mL	2.1972 mL	5.4931 mL
	15 mM	0.1465 mL	0.7324 mL	1.4648 mL	3.6620 mL
	20 mM	0.1099 mL	0.5493 mL	1.0986 mL	2.7465 mL
	25 mM	0.0879 mL	0.4394 mL	0.8789 mL	2.1972 mL
	30 mM	0.0732 mL	0.3662 mL	0.7324 mL	1.8310 mL
	40 mM	0.0549 mL	0.2747 mL	0.5493 mL	1.3733 mL
	50 mM	0.0439 mL	0.2197 mL	0.4394 mL	1.0986 mL
	60 mM	0.0366 mL	0.1831 mL	0.3662 mL	0.9155 mL
	80 mM	0.0275 mL	0.1373 mL	0.2747 mL	0.6866 mL
	100 mM	0.0220 mL	0.1099 mL	0.2197 mL	0.5493 mL