Palmitoyltransferase ZDHHC19

Definition:

Palmitoyltransferase that mediates palmitoylation of RRAS, leading to increased cell viability.; (Microbial infection) Promotes Chikungunya virus (CHIKV) replication by mediating viral nsp1 palmitoylation.

References:

[1]. Na Zhang, et al. Fatty Acid Synthase Promotes the Palmitoylation of Chikungunya Virus nsP1. J Virol. 2019 Jan 17;93(3):e01747-18. [Content Brief]

[2]. Florian Baumgart, et al. Palmitoylation of R-Ras by human DHHC19, a palmitoyl transferase with a CaaX box. Biochim Biophys Acta. 2010 Mar;1798(3):592-604. [Content Brief]

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