Protein NEDD1

Definition:

Required for mitosis progression. Promotes the nucleation of microtubules from the spindle.

References:

[1]. Hui Zhu, et al. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. J Cell Biol. 2008 Dec 1;183(5):835-48. [Content Brief]

[2]. Xiaoyan Zhang, et al. Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. J Cell Sci. 2009 Jul 1;122(Pt 13):2240-51. [Content Brief]

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