Protein orai-3

Definition:

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.

References:

[1]. Ivan Bogeski, et al. Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Sci Signal. 2010 Mar 30;3(115):ra24. [Content Brief]

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