Putative neuropeptide Y receptor type 6

Definition:

When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.

References:

[1]. M Matsumoto, et al. Inactivation of a novel neuropeptide Y/peptide YY receptor gene in primate species. J Biol Chem. 1996 Nov 1;271(44):27217-20. [Content Brief]

[2]. P Gregor, et al. Molecular characterization of a second mouse pancreatic polypeptide receptor and its inactivated human homologue. J Biol Chem. 1996 Nov 1;271(44):27776-81. [Content Brief]

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