Bis-5,5-Nortrachelogenin

Cat. No.: HY-N2939: FAQs
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Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM.

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Bis-5,5-Nortrachelogenin Chemical Structure

CAS No. : 870480-56-1

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Description	Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM^[1].
Molecular Weight	746.75
Formula	C₄₀H₄₂O₁₄
CAS No.	870480-56-1
SMILES	OC1=C(OC)C=C(C[C@@H]2[C@](O)(C(OC2)=O)CC3=CC(OC)=C(C=C3)O)C=C1C4=CC(C[C@@H]5[C@](O)(C(OC5)=O)CC6=CC(OC)=C(C=C6)O)=CC(OC)=C4O
Structure Classification	Phenylpropanoids Lignans
Initial Source	Plants Thymelaeaceae Wikstroemia indica
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Wang LY, et al. Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities. Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51. [Content Brief]

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis-5,5-Nortrachelogenin870480-56-1OthersBis-5,5-Nortrachelogenin 是从 Wikstroemia indica 根中分离得到的活性提取物。Bis-5,5-Nortrachelogenin 抑制脂多糖 (LPS) 和重组小鼠干扰素-γ (IFN-γ) 激活的小鼠巨噬细胞样细胞系 RAW 264.7 中一氧化氮 (NO) 的生成，IC₅₀ 值为 48.6 mM。Inhibitorinhibitorinhibit

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Bis-5,5-Nortrachelogenin