1. CGP 12177 hydrochloride

CGP 12177 hydrochloride  (Synonyms: (±)-CGP 12177 hydrochloride)

Cat. No.: HY-101393A Purity: 99.57%
COA Handling Instructions

CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery.

For research use only. We do not sell to patients.

CGP 12177 hydrochloride Chemical Structure

CGP 12177 hydrochloride Chemical Structure

CAS No. : 64208-32-8

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Description

CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery[1].

Molecular Weight

315.80

Formula

C14H22ClN3O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC2=C(OCC(O)CNC(C)(C)C)C=CC=C2N1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CGP 12177 hydrochloride
Cat. No.:
HY-101393A
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