2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Cisapride monohydrate

Cisapride monohydrate  (Synonyms: R 51619 monohydrate; (±)-Cisaprid monohydrate)

Cat. No.: HY-14149A
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Cisapride monohydrate is an orally and potent 5-HT4 receptor agonist and hERG inhibitor. Cisapride monohydrate is an prokinetic agent which facilitates or restores motility throughout the length of the gastrointestinal tract. Cisapride monohydrate stimulates gastrointestinal motor activity through an indirect mechanism involving the release of acetylcholine mediated by postganglionic nerve endings in the myenteric plexus of the gut.

For research use only. We do not sell to patients.

Cisapride monohydrate Chemical Structure

Cisapride monohydrate Chemical Structure

CAS No. : 260779-88-2

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Other In-stock Forms of Cisapride monohydrate:

Other Forms of Cisapride monohydrate:

Cisapride monohydrate Related Antibodies

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1 Publications Citing Use of MCE Cisapride monohydrate

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Description

Cisapride monohydrate is an orally and potent 5-HT4 receptor agonist and hERG inhibitor. Cisapride monohydrate is an prokinetic agent which facilitates or restores motility throughout the length of the gastrointestinal tract. Cisapride monohydrate stimulates gastrointestinal motor activity through an indirect mechanism involving the release of acetylcholine mediated by postganglionic nerve endings in the myenteric plexus of the gut[1][2].

IC50 & Target

5-HT4 Receptor

0.14 μM (EC50)

Clinical Trial
Molecular Weight

483.96

Formula

C23H31ClFN3O5
CAS No.
SMILES

ClC1=C(N)C=C(OC)C(C(N[C@H]2[C@@H](OC)CN(CCCOC3=CC=C(F)C=C3)CC2)=O)=C1.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cisapride monohydrate Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cisapride260779-88-2R 51619(±)-CisapridR51619R-516195-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorhuman ether-a-go-go-related genehERG5-HT4 agonistpatch-clampprokinetic agentgastrointestinalInhibitorinhibitorinhibit

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