2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. µ-Conotoxin GIIIB

μ-Conotoxin GIIIB is a 22-residue polypeptide that can be isolated from the venom of piscivorous cone snail Conus geographus. μ-Conotoxin GIIIB is a NaV1.4 channel inhibitor. μ-Conotoxin GIIIB blocks muscle cell's contraction.

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µ-Conotoxin GIIIB Chemical Structure

µ-Conotoxin GIIIB Chemical Structure

CAS No. : 140678-12-2

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µ-Conotoxin GIIIB Related Antibodies

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Description

μ-Conotoxin GIIIB is a 22-residue polypeptide that can be isolated from the venom of piscivorous cone snail Conus geographus. μ-Conotoxin GIIIB is a NaV1.4 channel inhibitor. μ-Conotoxin GIIIB blocks muscle cell's contraction[1][2][3].

IC50 & Target

NaV1.4 Channel[2]
Molecular Weight

2640.17

Formula

C101H175N39O30S7
CAS No.
Sequence

Arg-Asp-Cys-Cys-Thr-{Hyp}-{Hyp}-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-{Hyp}-Met-Lys-Cys-Cys-Ala (Disulfide bridge:Cys3-Cys15,Cys4-Cys20,Cys10-Cys21)
Sequence Shortening

RDCCT-{Hyp}-{Hyp}-RKCKDRRCK-{Hyp}-MKCCA (Disulfide bridge:Cys3-Cys15,Cys4-Cys20,Cys10-Cys21)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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µ-Conotoxin GIIIB Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

µ-Conotoxin GIIIB140678-12-2Sodium ChannelNa channelsNa+ channelsMuscle cellcontractionNa+ channeltoxinInhibitorinhibitorinhibit

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