2. Anti-infection
  3. Bacterial
  4. Duramycin

Duramycin  (Synonyms: Moli1901; Lancovutide)

Cat. No.: HY-106302 Purity: 99.46%
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Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF).

For research use only. We do not sell to patients.

Duramycin Chemical Structure

Duramycin Chemical Structure

CAS No. : 1391-36-2

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Based on 1 publication(s) in Google Scholar

Duramycin Related Antibodies

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Description

Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF)[1][2].

In Vivo

Evaluation of [68Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [68Ga]NODAGA-Duramycin. [68Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

2013.28

Formula

C89H125N23O25S3
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)
Sequence Shortening

CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)
SMILES

[CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)]
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 0.5 mg/mL (0.25 mM; Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.46%

COA (242 KB) RP-HPLC (265 KB)

Handling Instructions (2659 KB)
References
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Duramycin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Duramycin1391-36-2Moli1901 LancovutideMoli 1901Moli-1901BacterialLantibioticcysticfibrosispolypeptideprotein-lipidrespiratoryphosphatidylethanolaminelanthioninemethyllanthionineInhibitorinhibitorinhibit

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