1. Apoptosis
  2. Ferroptosis
  3. Ferroptosis-IN-3

Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation.

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Ferroptosis-IN-3 Chemical Structure

Ferroptosis-IN-3 Chemical Structure

CAS No. : 3017222-33-9

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Description

Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation[1].

Molecular Weight

286.71

Formula

C15H11ClN2O2

CAS No.
SMILES

OC1=C(C2=CC=C(O)C=C2)NN=C1C3=CC=C(Cl)C=C3

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Ferroptosis-IN-3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ferroptosis-IN-3
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HY-149670
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