2. Gene
  3. CEBPZ - CCAAT enhancer binding protein zeta Gene

CEBPZ - CCAAT enhancer binding protein zeta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CBF; CBF2; NOC1; HSP-CBF

Gene ID: 10153 | Gene type: protein coding

About CEBPZ

Cytogenetic location: 2p22.2 Genomic coordinates (GRCh38): 2:37,201,612-37,231,596 (from NCBI)

This gene has 3 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in testis (RPKM 27.1), adrenal (RPKM 18.8) and 25 other tissues.

Summary

This gene belongs to the CBF/Mak21 family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. [provided by RefSeq, Nov 2020]

CEBPZ Products(1)

mRNA Protein Name
NM_005760.3 NP_005751.2 CCAAT/enhancer-binding protein zeta

CEBPZ Protein Structure

CBF

CBF: CBF/Mak21 family (522 - 732)

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  • 1054 a.a.
Protein Preferred Names Protein Names

CCAAT/enhancer-binding protein zeta

CCAAT-box-binding transcription factor

Related Diseases

Diseases Alias
Opportunistic Bacterial Infectious Disease
Nocardiosis

Nocardia Infection

Nocardia Infections

Nocardia Infectious Disease

Lung Nocardiosis

Nocardiasis

Nocardiosis Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02450 CEBPZ Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CEBPZ VGNC VGNC:71082
Felis catus CEBPZ VGNC VGNC:60741
Mus musculus CEBPZ MGD MGI:109386
Canis familiaris CEBPZ VGNC VGNC:39090
Rattus norvegicus CEBPZ RGD RGD:1304994
Bos taurus CEBPZ VGNC VGNC:27164