2. Gene
  3. Parp10 - poly (ADP-ribose) polymerase family, member 10 Gene

Parp10 - poly (ADP-ribose) polymerase family, member 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 102548778 | Gene type: protein coding

About Parp10

Primary_assembly 7: 107,949,043-107,958,304 reverse strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 204 orthologues, 7 paralogues and is associated with 3 phenotypes. Biased expression in Spleen (RPKM 127.8), Adrenal (RPKM 115.4) and 9 other tissues.

Summary

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; pentosyltransferase activity; and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of macromolecule metabolic process; and protein ADP-ribosylation. Predicted to be located in Golgi apparatus; cytosol; and nucleolus. Predicted to be active in cytoplasm and nucleus. Orthologous to human PARP10 (poly(ADP-ribose) polymerase family member 10). [provided by Alliance of Genome Resources, Apr 2022]

Parp10 Products(4)

mRNA Protein Name
XM_039080533.1 XP_038936461.1 protein mono-ADP-ribosyltransferase PARP10 isoform X2
XM_006241910.4 XP_006241972.1 protein mono-ADP-ribosyltransferase PARP10 isoform X1
XM_039080534.1 XP_038936462.1 protein mono-ADP-ribosyltransferase PARP10 isoform X3
XM_039080535.1 XP_038936463.1 protein mono-ADP-ribosyltransferase PARP10 isoform X4

Parp10 Protein Structure

RRM1_2_PAR10

RRM1_2_PAR10: cd12547 (8 - 78)

RRM_SF

RRM_SF: cl17169 (193 - 241)

TCCD_inducible_PARP_like

TCCD_inducible_PARP_like: cd01439 (850 - 968)

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  • 977 a.a.
Protein Preferred Names Protein Names

protein mono-ADP-ribosyltransferase PARP10

poly [ADP-ribose] polymerase 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136979 RBN012759 Inhibitor 99.80% Unkown
HY-150207 RBN-3143 Inhibitor 99.24% Unkown
HY-123512 OUL35 Inhibitor 99.84% Unkown
HY-100225 ME0328 Inhibitor 99.59% Unkown
HY-143398 PARP10/15-IN-1 Inhibitor 95.00% Unkown
HY-148566 OUL232 Inhibitor 99.82% Unkown
HY-146502 PARP10/15-IN-3 Inhibitor 99.98% Unkown
HY-146501 PARP10/15-IN-2 Inhibitor 99.00% Unkown
HY-143338 ART-IN-1 Inhibitor 98.91% Unkown
HY-121719 TIQ-A Inhibitor 99.65% Unkown
HY-148754 PARP10-IN-3 Inhibitor 98.89% Unkown
HY-148709 ARTD10/PARP10-IN-1 Inhibitor / Unkown
HY-148710 ARTD10/PARP10-IN-2 Inhibitor / Unkown
HY-W294889 OUL245 Inhibitor / Unkown
HY-155993 YCH1899 Inhibitor / Unkown
HY-148753 PARP10-IN-2 Inhibitor 98.02% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Parp10 NCBI NCBI:84875