2. Gene
  3. NMUR1 - neuromedin U receptor 1 Gene

NMUR1 - neuromedin U receptor 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FM3; FM-3; GPC-R; GPR66; NMU1R; (FM-3)

Gene ID: 10316 | Gene type: protein coding

About NMUR1

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:231,518,455-231,530,445 (from NCBI)

This gene has 1 transcript (splice variant), 265 orthologues and 15 paralogues. Broad expression in fat (RPKM 2.5), lung (RPKM 1.6) and 20 other tissues.

Summary

Enables neuromedin U binding activity and neuromedin U receptor activity. Involved in several processes, including activation of Phospholipase C activity; chloride transport; and second-messenger-mediated signaling. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

NMUR1 Products(1)

mRNA Protein Name
NM_006056.5 NP_006047.3 neuromedin-U receptor 1

NMUR1 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (77 - 356)

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  • 426 a.a.
Protein Preferred Names Protein Names

neuromedin-U receptor 1

G-protein coupled receptor 66

Related Diseases

Diseases Alias
Spherocytosis, Type 3

Hereditary Spherocytosis Type 3

SPH3

Hs3

Spherocytosis, Hereditary, 3

Hereditary Spherocytosis 3

Spherocytosis 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09392 NMUR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NMUR1 VGNC VGNC:99388
Felis catus NMUR1 VGNC VGNC:67438
Mus musculus NMUR1 MGD MGI:1341898
Rattus norvegicus NMUR1 RGD RGD:619867
Bos taurus NMUR1 VGNC VGNC:32140
Canis familiaris NMUR1 VGNC VGNC:59087