SCML2 - Scm polycomb group protein like 2 Gene

Homo sapiens

Gene ID: 10389 | Gene type: protein coding

About SCML2

Cytogenetic location: Xp22.13 Genomic coordinates (GRCh38): X:18,239,313-18,355,118 (from NCBI)

This gene has 5 transcripts (splice variants), 279 orthologues and 18 paralogues. Broad expression in testis (RPKM 5.8), adrenal (RPKM 1.8) and 19 other tissues.

Summary

This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone Peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010]

SCML2 Products(1)

mRNA	Protein	Name
NM_006089.3	NP_006080.1	sex comb on midleg-like protein 2

SCML2 Protein Structure

MBT

SLED

SAM_1

0
200
400
600
700 a.a.

Protein Preferred Names

Protein Names

sex comb on midleg-like protein 2

sex comb on midleg like 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12517	SCML2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SCML2	VGNC	VGNC:76979
Canis familiaris	SCML2	VGNC	VGNC:45911
Bos taurus	SCML2	VGNC	VGNC:34341
Rattus norvegicus	SCML2	RGD	RGD:1564289
Felis catus	SCML2	VGNC	VGNC:82309
Mus musculus	SCML2	MGD	MGI:1340042

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