OLFM4 - olfactomedin 4 Gene

Homo sapiens

Also known as GC1; OLM4; OlfD; GW112; hGC-1; hOLfD; UNQ362; bA209J19.1

Gene ID: 10562 | Gene type: protein coding

About OLFM4

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:53,028,813-53,052,057 (from NCBI)

This gene has 1 transcript (splice variant), 250 orthologues and 9 paralogues. Biased expression in small intestine (RPKM 721.2), duodenum (RPKM 639.8) and 4 other tissues.

Summary

This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011]

OLFM4 Products(1)

mRNA	Protein	Name
NM_006418.5	NP_006409.3	olfactomedin-4 precursor

OLFM4 Protein Structure

OLF

0
100
200
300
400
510 a.a.

Protein Preferred Names

Protein Names

olfactomedin-4

G-CSF-stimulated clone 1 protein

Recombinant OLFM4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71179	OLFM4 Protein, Human (HEK293, His)	Q6UX06 (D21-Q510)	≥95%

Related Diseases

Diseases

Alias

Pancreatic Cancer

Pancreatic Carcinoma	Carcinoma Of Pancreas
Familial Pancreatic Carcinoma	Pancreatic Neoplasm
Pancreatic Carcinoma, Familial	Malignant Neoplasm Of Pancreas
Pancreatic Acinar Carcinoma	Pancreatic Tumor
Familial Pancreatic Cancer	Neoplasm Of The Pancreas
Cancer Of The Pancreas	Pancreatic Carcinoma, Somatic
Pancreatic Cancer, Somatic	Ca Body Of Pancreas
Ca Head Of Pancreas	Ca Tail Of Pancreas
Malignant Neoplasm Of Body Of Pancreas	Malignant Neoplasm Of Head Of Pancreas
Malignant Neoplasm Of Tail Of Pancreas	Pancreas Neoplasm
Exocrine Cancer	Exocrine Pancreas Carcinoma
Hereditary Pancreatic Cancer	Hereditary Pancreatic Carcinoma
PNCA	Pancreatic Cancer, Susceptibility To
Carcinoma Of Head Of Pancreas	Pancreatic Neoplasms
Pancreatic Tumors	Cancer, Pancreatic
Cancer Of Pancreas	Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Atrophy Of Prostate

Colonic Benign Neoplasm

Colon Neoplasm	Colonic Mass
Colonic Tumor	Neoplasm Of Colon
Neoplasm Of The Colon	Colonic Neoplasms
Colon Cancer	Colon Carcinoma Nos
Colonic Cancer	Metastatic Colon Cancer Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09773	OLFM4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	OLFM4	VGNC	VGNC:75418
Rattus norvegicus	OLFM4	RGD	RGD:1311708
Canis familiaris	OLFM4	VGNC	VGNC:49706
Bos taurus	OLFM4	VGNC	VGNC:32420
Felis catus	OLFM4	VGNC	VGNC:63961
Mus musculus	OLFM4	MGD	MGI:2685142
Others	OLFM4	NCBI

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