SCGN - secretagogin, EF-hand calcium binding protein Gene

Homo sapiens

Also known as SEGN; CALBL; SECRET; setagin; DJ501N12.8

Gene ID: 10590 | Gene type: protein coding

About SCGN

Cytogenetic location: 6p22.2 Genomic coordinates (GRCh38): 6:25,652,215-25,701,783 (from NCBI)

This gene has 2 transcripts (splice variants), 267 orthologues and 2 paralogues. Biased expression in stomach (RPKM 11.2), colon (RPKM 8.7) and 8 other tissues.

Summary

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]

SCGN Products(1)

mRNA	Protein	Name
NM_006998.4	NP_008929.2	secretagogin

SCGN Protein Structure

EF-hand_7

EF-hand_5

0
100
200
276 a.a.

Protein Preferred Names

Protein Names

secretagogin

Recombinant SCGN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71042	SCGN Protein, Human (HEK293, His)	O76038 (M1-P276)	≥95%
HY-P76050	SCGN Protein, Human (His)	O76038 (D2-P276)	≥95%

Related Diseases

Diseases

Alias

Insulinoma

Islet Cell Adenoma	Insulin-Producing Tumor Of Islet Cells
Adenoma Islet Cell	Islet Cell Tumor
Experimental Organism Islet Cell Adenoma Neoplasm

Fanconi Renotubular Syndrome 2

FRTS2

Fanconi Renotubular Syndrome, Type 2

Neuroendocrine Tumor

Neuroendocrine Neoplasm	Neuroendocrine Tumors
Carcinoma, Neuroendocrine

Central Neurocytoma

Neurocytoma	Neurolipocytoma
Neurocytoma Central

Labyrinthitis

Labyrinthine Disorder	Inner Ear Inflammation
Otitis Interna	Labyrinth Hyperaemia

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12509	SCGN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SCGN	VGNC	VGNC:77030
Bos taurus	SCGN	VGNC	VGNC:34337
Rattus norvegicus	SCGN	RGD	RGD:1303281
Canis familiaris	SCGN	VGNC	VGNC:45909
Mus musculus	SCGN	MGD	MGI:2384873
Felis catus	SCGN	VGNC	VGNC:64913
Others	SCGN	NCBI