UTP14A - UTP14A small subunit processome component Gene

Homo sapiens

Also known as Utp14; NYCO16; SDCCAG16; dJ537K23.3

Gene ID: 10813 | Gene type: protein coding

About UTP14A

Cytogenetic location: Xq26.1 Genomic coordinates (GRCh38): X:129,906,164-129,929,752 (from NCBI)

This gene has 4 transcripts (splice variants), 230 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 5.9), appendix (RPKM 5.8) and 25 other tissues.

Summary

This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

UTP14A Products(2)

mRNA	Protein	Name
NM_001166221.2	NP_001159693.1	U3 small nucleolar RNA-associated protein 14 homolog A isoform 2
NM_006649.4	NP_006640.2	U3 small nucleolar RNA-associated protein 14 homolog A isoform 1

UTP14A Protein Structure

Utp14

0
200
400
600
771 a.a.

Protein Preferred Names

Protein Names

U3 small nucleolar RNA-associated protein 14 homolog A

UTP14, U3 small nucleolar ribonucleoprotein, homolog A

Related Diseases

Diseases

Alias

Bowen-Conradi Syndrome

BWCNS	Bowen Hutterite Syndrome
Bowen-Conradi Hutterite Syndrome	Bowen Syndrome, Hutterite Type
Bowen Hutterite Syndrome, Formerly	Hutterite Syndrome
Bowen Syndrome Hutterite Type	Fetal Growth Retardation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15575	UTP14A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	UTP14A	RGD	RGD:1359313
Mus musculus	UTP14A	MGD	MGI:1919804
Macaca mulatta	UTP14A	VGNC	VGNC:103882

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