2. Gene
  3. GPR83 - G protein-coupled receptor 83 Gene

GPR83 - G protein-coupled receptor 83 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as GIR; GPR72

Gene ID: 10888 | Gene type: protein coding

About GPR83

Cytogenetic location: 11q21 Genomic coordinates (GRCh38): 11:94,377,316-94,401,419 (from NCBI)

This gene has 2 transcripts (splice variants), 207 orthologues and 33 paralogues. Biased expression in brain (RPKM 1.9), thyroid (RPKM 1.3) and 4 other tissues.

Summary

Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within response to glucocorticoid. Located in cilium. [provided by Alliance of Genome Resources, Apr 2022]

GPR83 Products(2)

mRNA Protein Name
NM_001330345.2 NP_001317274.1 G-protein coupled receptor 83 isoform 2 precursor
NM_016540.4 NP_057624.3 G-protein coupled receptor 83 isoform 1 precursor

GPR83 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (88 - 345)

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  • 423 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 83

G-protein coupled receptor 72

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P2278 PEN (human) Agonist 99.68% Unkown
HY-P2277 PEN (rat) Agonist / Unkown
HY-P2277A PEN (rat) (TFA) Agonist / Unkown
HY-RS05737 GPR83 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GPR83 VGNC VGNC:67440
Rattus norvegicus GPR83 RGD RGD:619891
Mus musculus GPR83 MGD MGI:95712
Canis familiaris GPR83 VGNC VGNC:41445
Bos taurus GPR83 VGNC VGNC:29600
Macaca mulatta GPR83 VGNC VGNC:73142