2. Gene
  3. HNRNPA0 - heterogeneous nuclear ribonucleoprotein A0 Gene

HNRNPA0 - heterogeneous nuclear ribonucleoprotein A0 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HNRPA0

Gene ID: 10949 | Gene type: protein coding

About HNRNPA0

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:137,745,651-137,754,363 (from NCBI)

This gene has 1 transcript (splice variant), 139 orthologues and 36 paralogues.

Summary

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008]

HNRNPA0 Products(1)

mRNA Protein Name
NM_006805.4 NP_006796.1 heterogeneous nuclear ribonucleoprotein A0

HNRNPA0 Protein Structure

(9 - 78)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (100 - 168)

  • 0
  • 100
  • 200
  • 305 a.a.
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein A0

hnRNA binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06260 HNRNPA0 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus HNRNPA0 VGNC VGNC:52238
Mus musculus HNRNPA0 MGD MGI:1924384
Canis familiaris HNRNPA0 VGNC VGNC:51722
Rattus norvegicus HNRNPA0 RGD RGD:1563684