2. Gene
  3. LILRA3 - leukocyte immunoglobulin like receptor A3 Gene

LILRA3 - leukocyte immunoglobulin like receptor A3 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4

Gene ID: 11026 | Gene type: protein coding

About LILRA3

Cytogenetic location: 19q13.4 Genomic coordinates (GRCh38): 19:50,900,001-58,617,616

Summary

This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]

LILRA3 Products(2)

mRNA Protein Name
NM_001172654.2 NP_001166125.1 leukocyte immunoglobulin-like receptor subfamily A member 3 isoform 2 precursor
NM_006865.4 NP_006856.3 leukocyte immunoglobulin-like receptor subfamily A member 3 isoform 1 precursor

LILRA3 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (45 - 135)

Ig_3

Ig_3: Immunoglobulin domain (141 - 216)

Ig_2

Ig_2: Immunoglobulin domain (242 - 334)

Ig_3

Ig_3: Immunoglobulin domain (343 - 417)

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  • 456 a.a.
Protein Preferred Names Protein Names

leukocyte immunoglobulin-like receptor subfamily A member 3

CD85 antigen-like family member E

Recombinant LILRA3 Proteins

Cat. No. Product Name Accession Purity
HY-P70162 ILT6 Protein, Human (HEK293, His) AAH28208.1 (T19-E439) ≥95%
HY-P72393 LILRA3/CD85e/ILT6 Protein, Human (Biotinylated, HEK293, His-Avi) AAH28208.1 (G24-E439) ≥95%
HY-P77984 LILRA3/CD85e/ILT6 Protein, Human (HEK293, His-Avi) Q8N6C8 (G24-E439) ≥95%
HY-P700776 LILRA3/CD85e/ILT6 Protein, Human (Biotinylated, HEK293, C-His-Avi) Q8N6C8 (G24-E439) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07647 LILRA3 Human Pre-designed siRNA Set A / Unkown