1. Gene
  2. NUDT21 - nudix hydrolase 21 Gene

NUDT21 - nudix hydrolase 21 Gene

Homo sapiens

Also known as CPSF5; CFIM25

Gene ID: 11051 | Gene type: protein coding

About NUDT21

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,429,133-56,451,332 (from NCBI)

This gene has 7 transcripts (splice variants) and 230 orthologues. Ubiquitous expression in brain (RPKM 30.7), ovary (RPKM 29.1) and 25 other tissues.

Summary

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]

NUDT21 Products(1)

mRNA Protein Name
NM_007006.3 NP_008937.1 cleavage and polyadenylation specificity factor subunit 5

NUDT21 Protein Structure

NUDIX_2

NUDIX_2: Nucleotide hydrolase (36 - 222)

  • 0
  • 100
  • 200
  • 227 a.a.
Protein Preferred Names Protein Names

cleavage and polyadenylation specificity factor subunit 5

CPSF 25 kDa subunit

Orthologs Information

Species Symbol Source ID
Bos taurus NUDT21 VGNC VGNC:32336
Rattus norvegicus NUDT21 RGD RGD:1305766
Macaca mulatta NUDT21 VGNC VGNC:99533
Mus musculus NUDT21 MGD MGI:1915469
Felis catus NUDT21 VGNC VGNC:97541