DDX52 - DExD-box helicase 52 Gene

Homo sapiens

Also known as ROK1; HUSSY19

Gene ID: 11056 | Gene type: protein coding

About DDX52

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:37,609,739-37,643,446 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 200 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 4.2), endometrium (RPKM 4.1) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

DDX52 Products(2)

mRNA	Protein	Name
NM_001291476.2	NP_001278405.1	probable ATP-dependent RNA helicase DDX52 isoform 2
NM_007010.5	NP_008941.3	probable ATP-dependent RNA helicase DDX52 isoform 1

DDX52 Protein Structure

DEAD

Helicase_C

0
100
200
300
400
500
599 a.a.

Protein Preferred Names

Protein Names

probable ATP-dependent RNA helicase DDX52

DEAD (Asp-Glu-Ala-Asp) box polypeptide 52

Related Diseases

Diseases

Alias

Chromosome 17q12 Deletion Syndrome

17q12 Microdeletion Syndrome	Del(17)(Q12)
Monosomy 17q12

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03657	DDX52 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	DDX52	VGNC	VGNC:27975
Mus musculus	DDX52	MGD	MGI:1925644
Macaca mulatta	DDX52	VGNC	VGNC:71679
Felis catus	DDX52	VGNC	VGNC:61414
Rattus norvegicus	DDX52	RGD	RGD:621743

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