TBC1D8 - TBC1 domain family member 8 Gene

Homo sapiens

Also known as AD3; VRP; HBLP1; GRAMD8; TBC1D8A

Gene ID: 11138 | Gene type: protein coding

About TBC1D8

This gene has 10 transcripts (splice variants), 197 orthologues and 45 paralogues. Ubiquitous expression in testis (RPKM 11.3), heart (RPKM 10.6) and 25 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

TBC1D8 Products(2)

mRNA	Protein	Name
NM_001102426.3	NP_001095896.1	TBC1 domain family member 8 isoform 2
NM_001330348.2	NP_001317277.1	TBC1 domain family member 8 isoform 1

TBC1D8 Protein Structure

GRAM

RabGAP-TBC

0
200
400
600
800
1000
1140 a.a.

Protein Preferred Names

Protein Names

TBC1 domain family member 8

BUB2-like protein 1

Related Diseases

Diseases

Alias

Autosomal Dominant Nonsyndromic Deafness 78

Dfna78

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14247	TBC1D8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS14248	TBC1D8B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TBC1D8	VGNC	VGNC:65989
Canis familiaris	TBC1D8	VGNC	VGNC:47151
Bos taurus	TBC1D8	VGNC	VGNC:35645
Macaca mulatta	TBC1D8	VGNC	VGNC:78153
Rattus norvegicus	TBC1D8	RGD	RGD:1595491
Mus musculus	TBC1D8	MGD	MGI:1927225

Name
Email *

	Sorry, but the email address you supplied was invalid.