SHLD3 - shieldin complex subunit 3 Gene

Homo sapiens

Also known as RINN1; CTC-534A2.2

Gene ID: 112441434 | Gene type: protein coding

About SHLD3

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,625,027-65,630,928 (from NCBI)

This gene has 2 transcripts (splice variants) and 92 orthologues.

Summary

Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]

SHLD3 Products(1)

mRNA	Protein	Name
NM_001365341.2	NP_001352270.1	shieldin complex subunit 3

Protein Preferred Names

Protein Names

shieldin complex subunit 3

REV7-interacting novel NHEJ regulator 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12875	SHLD3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SHLD3	RGD	RGD:41350418
Mus musculus	SHLD3	MGD	MGI:6194609

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