GPR45 - G protein-coupled receptor 45 Gene

Homo sapiens

Also known as PSP24; PSP24A; PSP24(ALPHA)

Gene ID: 11250 | Gene type: protein coding

About GPR45

Cytogenetic location: 2q12.1 Genomic coordinates (GRCh38): 2:105,241,743-105,243,467 (from NCBI)

This gene has 1 transcript (splice variant), 172 orthologues, 3 paralogues and is associated with 1 phenotype.

Summary

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008]

GPR45 Products(1)

mRNA	Protein	Name
NM_007227.3	NP_009158.3	probable G-protein coupled receptor 45

GPR45 Protein Structure

7tm_1

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

probable G-protein coupled receptor 45

PSP24-1

Related Diseases

Diseases

Alias

Diversion Colitis

Vascular Parkinsonism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05716	GPR45 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GPR45	VGNC	VGNC:73137
Bos taurus	GPR45	VGNC	VGNC:29588
Rattus norvegicus	GPR45	RGD	RGD:1306253
Felis catus	GPR45	VGNC	VGNC:67430
Canis familiaris	GPR45	VGNC	VGNC:41436
Mus musculus	GPR45	MGD	MGI:2135882

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