FILIP1L - filamin A interacting protein 1 like Gene

Homo sapiens

Also known as DOC1; DOC-1; GIP90; GIP130

Gene ID: 11259 | Gene type: protein coding

About FILIP1L

Cytogenetic location: 3q12.1 Genomic coordinates (GRCh38): 3:99,828,811-100,114,501 (from NCBI)

This gene has 10 transcripts (splice variants), 265 orthologues and 3 paralogues. Ubiquitous expression in gall bladder (RPKM 44.5), urinary bladder (RPKM 29.8) and 23 other tissues.

Summary

Predicted to be located in cytoplasm; membrane; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FILIP1L Products(9)

mRNA	Protein	Name
NM_001042459.3	NP_001035924.1	filamin A-interacting protein 1-like isoform 3
NM_001282793.2	NP_001269722.1	filamin A-interacting protein 1-like isoform 4
NM_001282794.2	NP_001269723.1	filamin A-interacting protein 1-like isoform 5
NM_001370247.1	NP_001357176.1	filamin A-interacting protein 1-like isoform 2
NM_001387850.1	NP_001374779.1	filamin A-interacting protein 1-like isoform 6
NM_001387851.1	NP_001374780.1	filamin A-interacting protein 1-like isoform 7
NM_001387852.1	NP_001374781.1	filamin A-interacting protein 1-like isoform 8
NM_014890.4	NP_055705.2	filamin A-interacting protein 1-like isoform 2
NM_182909.4	NP_878913.2	filamin A-interacting protein 1-like isoform 1

FILIP1L Protein Structure

CortBP2

0
200
400
600
800
1000
1135 a.a.

Protein Preferred Names

Protein Names

filamin A-interacting protein 1-like

130 kDa GPBP-interacting protein

Related Diseases

Diseases

Alias

Ovarian Cancer 1

Ovarian Cancer, Susceptibility To	Ovarian Cancer, Susceptibility To, 1
OVCAS1	Ovarian Cancer
Ovarian Carcinoma	Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Macular Degeneration, Age-Related, 1

Macular Degeneration	Age-Related Macular Degeneration
Macular Degeneration, Age-Related	Age Related Macular Degeneration
Age Related Macular Degeneration 1	ARMD1
Senile Macular Degeneration	Maculopathy, Age-Related, 1
Macular Degeneration, Age-Related, Reduced Risk Of	Age Related Maculopathy 1
Age Related Maculopathies	Age Related Maculopathy
Senile Macular Retinal Degeneration	Macular Degeneration Of Retina
Age-Related Maculopathy	Amd
Armd	Age-Related Maculopathy, Susceptibility To
Maculopathy Age-Related	Macular Degeneration, Age-Related, 1, Susceptibility To
Maculopathy, Age-Related	Macular Degeneration, Age-Related, Type 1
Macular Degeneration, Age-Related, 2

Cerebrooculofacioskeletal Syndrome 1

Cofs Syndrome	COFS1
Pena-Shokeir Syndrome Type 2	Cofs
Pena-Shokeir Syndrome, Type Ii	Cerebrooculofacioskeletal Syndrome
Cerebro-Oculo-Facio-Skeletal Syndrome 1	Pena Shokeir Syndrome Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04949	FILIP1L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FILIP1L	VGNC	VGNC:29013
Mus musculus	FILIP1L	MGD	MGI:1925999
Rattus norvegicus	FILIP1L	RGD	RGD:1565927
Canis familiaris	FILIP1L	VGNC	VGNC:40882
Macaca mulatta	FILIP1L	VGNC	VGNC:72562
Felis catus	FILIP1L	VGNC	VGNC:62274

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